منابع مشابه
The enzymatic desulfation of sulfated sugar nucleotides by a novel sulfatase in hen oviduct.
A soluble fraction from the isthmus region of hen oviduct catalyzes the liberation of SOF from UDP-N-acetylgalactosamine-4-sulfate (the nucleotide that accumulates in the same tissue during egg formation). The enzyme is purified some &fold and is shown to catalyze the reactions: (a) UDP-N-acetylgalactosamine-4-sulfate 4 UDP-N-acetylgalactosamine plus SOF; and (b) UDP-N-acetylgalactosamine-4,6-d...
متن کاملMild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides.
Sulfated fucans from marine invertebrates have simple, linear structures, composed of repeating units of oligosaccharides. Most of these polysaccharides contain 3-linked fucosyl units, but each species of invertebrate has a specific pattern of sulfation. No specific enzyme able to cleave or to desulfate these polysaccharides has been described yet. Therefore, we employed an alternative approach...
متن کاملSynthesis and Anticoagulant Activity of Polyureas Containing Sulfated Carbohydrates
Polyurea-based synthetic glycopolymers containing sulfated glucose, mannose, glucosamine, or lactose as pendant groups have been synthesized by step-growth polymerization of hexamethylene diisocyanate and corresponding secondary diamines. The obtained polymers were characterized by gel permeation chromatography, nuclear magnetic resonance spectroscopy, and Fourier transform infrared spectroscop...
متن کاملDesulfation on the cell surface
esults on page 257 by Soulet and Rivest implicate polyamines in controlling immune responses in the brain. Their results suggest that polyamine synthesis, if left unchecked, can cause damaging inflammatory responses reminiscent of neurodegenerative disorders. Recognition of bacterial and viral pathogens by microglial cells, the brain’s equivalent of macrophages, elicits a cascade of gene expres...
متن کاملBinding of sperm to somatic cells via HLA-DR. Modulation by sulfated carbohydrates.
We have shown previously that human sperm bind and enter leukocytes expressing surface HLA class II molecules. In the present study, mutant B lymphoblastoid cells and HLA-DR-transfected murine 3T3 fibroblasts are used to confirm that HLA class II molecules are somatic cell receptors for sperm. Further, for isolated HLA-DR expressed on murine cells, we show that sperm receptor activity requires ...
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ژورنال
عنوان ژورنال: Trends in Glycoscience and Glycotechnology
سال: 2002
ISSN: 0915-7352,1883-2113
DOI: 10.4052/tigg.14.343